Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs
نویسندگان
چکیده
منابع مشابه
Suppressive Mechanisms Induced by Tregs in Celiac Disease
Celiac disease (CD) is a systemic immune-mediated disorder caused by the dietary gluten in individuals who are genetically susceptible to the disease. In fact, CD is a T cell-mediated immune disease in which gluten-derived peptides activate the lamina propria CD4+ Teff cells, and these T-cell subsets can cause the intestinal tissue damages. Also, there are additional subsets of CD4+ T cells wit...
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I N ADDITION to immunosuppression. complex and for the most part similar metabolic effects are caused by cyclosporine (CyA) and FK 506. even though these drugs are chemically unrelated and have different cytosolic binding sites (called immunophilins) (Table I). One of the striking nonimmunological effects of Cy A and FK S06 is hepatocyte proliferation. which can be demonstrated in the in vivo m...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2009
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfp586